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Peptides are an important topic in skin care these days due to their ability to restore tone and texture to aging skin. It’s no secret that over time, skin loses its resiliency. This loss of elasticity results in visible fine lines, wrinkles and an uneven surface. To make matters worse, many of us are constantly exposed to external contributors like pollution, stress and the sun which are just as detrimental to the health of our skin as time.

Aging and environmental factors cause our skin to produce less and less collagen. It’s collagen that actually supports the structure of our skin, making it firm and resilient. Peptides (fragments of proteins) have the unique ability to stimulate collagen production, allowing our skin to regain lost vitality and slow the onset of further signs of aging.

Peptides can help strengthen the skin, repair damage, smooth wrinkles, even out skin tone and restore clarity.



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Face-firming Peptides (Tetra and Pentapeptides) boost new collagen production to recondition the outer most layer of the skin. Collagen is a protein that plays an important role when it comes to maintaining a firm, even complexion. Matrixyl, another name for Palmitoyl Pentapeptide-3, is a predominant face-firming peptide... Matrixyl is found in:



Boscia Restorative Amino-3P Firming Treatment $48


An advanced, age-defying treatment that improves your skin to a more youthful look and feel with pure and select botanicals.

A powerful antioxidant, Jojoba Leaf, and Palmitoyl Penta-Peptide, an effective combined amino acid, help defend against damage and promote smoother, more resilient skin.

Aloe Leaf promotes healthy cell renewal. Encapsulated Vitamin A, refines your skin's texture to diminish the appearance of fine lines. Encapsulated Panthenol-Vitamin B5 and a unique anti-irritant, Willow Herb, comfort and soothe your sensitivities.




Philosophy When Hope Is Not Enough Serum $38

When hope is not enough serum was created to help fight the signs of aging associated with midlife. The unique formula is a light, fluid gel enriched with toning, firming, hydrating and anti-wrinkle properties. Their formula contains a unique blend of antioxidants that help to restore skin cells and reduce the signs of environmental damage.

You need this product if:

- your skin has lost its radiance.
- your skin needs firmness and lift.
- you want to hydrate the skin without adding oil.
- you want to revitalize stressed, aged, wrinkled skin.
- you want to guard the skin from free-radical damage.
- you want to help diminish the appearance of unwanted hair.



Topix Replenix AE Dermal Restructuring Therapy $104

Topix Replenix AE Dermal Restructuring Therapy cosmetically enhances rebuilding of the skin from beneath and protects the renewed skin from further stress and damage. This rich cream formulation provides intensive skin moisturization, treatment and maintenance.

Benefits:

- Palmitoyl Pentapeptide-3 corrects wrinkles and fine lines by supporting new collagen growth.
- Green and White Tea polyphenols and potent antioxidants protect collagen from environmental damage.
- Sodium Hyaluronate intensively hydrates and plumps the dermis.
- Supports cellular oxygenation, triggering repair.
- Ceramide 2 replenishes lipids and maintains the barrier function of the skin.






Quintessence Q-Strixin Micro-Active Emulsion $88


The superior wrinkle reducing ingredients are the key to the benefits of Q-Strixin, Micro-Active Emulsion. Studies presented at the 20th World Congress of Dermatology, on July 2, 2002, document that the key effective ingredients, Palmitoyl Pentapeptide-3 (Pal-KTTKS) and Palmitoyl Oligopeptide are known to stimulate cell growth, reduce depth, length and volume of wrinkles, increase skin thickness, decrease overall skin roughness, helps correct discoloration and repairs sun damaged skin.

Palmitoyl Pentapeptide-3 , originally used in wound healing, this ingredient consists of a group of amino acids linked together attached to a fatty acid structurally related to the precursors of collagen type 1. Researchers recently found that when added to a culture of skin cells, Palmitoyl Pentapeptide-3 stimulates the synthesis of the key constituents of the skin matrix: collagen, elastin and glycosaminoglycans. Clinical studies have shown a dramatic improvement in skin smoothness and decreased wrinkle depth in test subjects.

More importantly,Palmitoyl Pentapeptide-3 proved to be even more effective than Retinol or vitamin C in reducing fine lines and wrinkles associated with photo-aged skin. A four-month study comparing Palmitoyl Pentapeptide-3 to Retinol, showed the peptide yielded similar dermal thickening as the Retinol, but without any negative side effects.

Palmitoyl Oligopeptide is a synthetic protein, made up of a fragment of collagen and palmitic acid. The palmitic acid is used to make collagen more lipophillic and make it more compatible with the human skin. Developed through intensive research, Palmitoyl Oligopeptide was the result of an effort to create a substance that would act like retinoic acid without the negative characteristics and irritation. The following statistics were gathered using image analysis of volunteers who used creams containing a 3% concentration of Palmitoyl Oligopeptide for 28 days.

- Surface roughness Reduced 17%
- Mean depth of wrinkles Reduced 23%
- Depth of main wrinkle Reduced 39%
- Skin thickness Increased 4%

Photo aged skin occurs when the underlying collagen and elastin support breaks down from sun exposure. This results in the skins’ foundation becoming stiff and hard with age. The ingredients in Q-Strixin can spark new growth at the cellular level, thus increasing the production of new collagen and elastin – rebuilding your skin’s foundation from the ground up.



Photolagen AGF by AminoGenesis $89


Photolagen is a giant leap forward in the evolution of skin care technology. After years of research and testing this formula has produced dramatic results for a wide range of skin concerns, including wrinkles, dryness, discoloration, skin firmness and texture.

Photolagen is unique in that it combines 3 proven technologies in one powerful serum. First the delivery system transports vital moisture deep into your skin. Next 17 amino acids go to work increasing collagen and elastin production. Lastly, the patented peptide technology immediately begins repairing and beautifying the surface of your skin. The end result is healthy, vibrant and more beautiful skin!

1 - An Award Winning Delivery System:

This proprietary, water based transport system is able to penetrate the skin and deliver amino acids, humectants, nutrients and moisture deep into the skin. In order to ensure rapid and complete penetration these important criteria have been met
- All ingredients used must be capable of penetrating the stratum corneum, the protective barrier of the skin
- The emulsion to be transported must be of correct molecular size and weight to dissipate into the skin
- Electro-static properties must be correct
- Controlled viscosity ensures maximum penetration


2 – The Amazing Power of Amino Acids

Amino acids are the building blocks of all living tissue on Earth. These basic building blocks are essential for normal cellular function. Photolagen-AGF contains 17 plant derived amino acids. Topical use of amino acids has shown to:
- Dramatically Help Moisture Content
- Decrease the Appearance of Wrinkles
- Promote Collagen and Elastin Production
- Help Regulate Sebaceous Gland Activity
- Decrease Discoloration Due to Sun Damage
- Improve Skin Texture and Feel

3 - Patented Pentapeptide Technology

Clinical trials prove the effectiveness of the Pal-KTTS Peptide at the World Congress of Dermatology in Paris in July of 2002, superior wrinkle reducing and sun damage repair abilities of the Pal-KTTS peptide as compared to traditional anti-aging retinoids was announced.

In Vitro studies show this peptide stimulates the following:
- Wrinkle Fighting Collagen Type I By 117%
- Firming (Anti sagging) Collagen Type IV By 357%
- Moisture Holding, Dermal Thickening Glycosaminoglycans by 267%

Further clinical trials showed the following:
- A Reduction of the Surface Area of Wrinkles By 68%
- An Average Reduction in Furrow Density of 46%
- A Reduction of Skin Roughness by 16%

Photolagen is for all skin types, doctor approved, hospital tested, PH balanced, hypoallergenic and non-comedogenic.




June Jacobs Elastin Collagen Serum $124


A powerful, age-defying, anti-wrinkle serum that helps repair damaged cells and dramatically firm and hydrate the skin. With continued use, this serum helps soften the appearance of fine lines and wrinkles and recontours epidermal cells for vibrant, resilient, younger-looking skin. Technologically advanced Matrixyl, a skin-tightening lipopeptide, stimulates the matrix molecules in the skin to promote collagen and elastin production. June Jacobs Elastin Collagen Serum encourages skin tissue to restore itself to more youthful resilience, while promoting deep repair and significantly reducing the appearance of wrinkles and facial laxity. Collagen-stimulating Vitamin C, superior marine-derived Collagen, Co-Q10, Tyrosine, botanicals antioxidants (from Grape Seed Extract, Green Tea, and Rose Hips), and an advanced combination of bioavailable hydrators synergistically deliver gradual, continual results. Provides superior moisture-retention, wrinkle relief and skin firming action, leaving the skin plumped, taut, moist, and glowing.



Wrinkle-relaxing Peptides (Hexapeptides) calm the muscle contractions that can cause expression lines and deep furrows. The results are not unlike Botox® injections, but without Botox‘s® side effects. Argireline is another name for Acetyl Hexapeptide-3, a predominant wrinkle-relaxing peptide. Argireline is found in:




Janson Beckett AlphaDerma CE $109


For best results use with: DermaExcel 7

Unique anti-aging wrinkle cure concentrate. Ideal for fine lines under & next to eye area (crows feet), wrinkles on the forehead (frown lines) and any other place fine lines & wrinkles are present.

The clinical ingredients in AlphaDerma CE are what make it so effective. ACETYL HEXAPEPTIDE-AH3(ARGIRELINE) relaxes facial muscle contractions to smooth out fine lines and depth of wrinkles. ALPHA LIPOIC ACID, VITAMIN C ESTER and DMAE is already recognized as a clinical treatment to combat skin aging.

- ALPHA LIPOIC ACID, the most potent antioxidant on the market today, helps repair aged skin while preventing future damage.
- VITAMIN C ESTER (ascorbyl palmitate) boosts protective antioxidant action and helps repair past damage by aiding new collagen production.
- DMAE often called “facelift in a jar”, helps Firm and Tighten the skin.
- ELASTIN is the main ingredient in the skin that allows it to stretch without leaving marks. AlphaDerma CE contains 100% rare, costly, freeze-dried powdered ELASTIN concentrate – which has almost 100% amino acid content. This makes our ELASTIN 10x more potent than any other standard ELASTIN products used in the U.S. or abroad.
- COLLAGEN is an integral part of the support structure of the skin. The addition of our collagen to the formulation plumps up the skin and helps fill in unwanted Fine lines and Wrinkles.
- SOY is a natural nutrient when taken internally; with the addition of our patented topical Soy Extract to our formulation the skin is given the nutrients it needs for healthier, younger-looking skin.

Prevent and Remove Stretchmarks and Scars:
One of a kind Stretchmark and Scar Treatment. We have three layers of skin: the epidermis, or outer layer; the dermis, or middle layer; and the subcutaneous stratum, or deepest layer. Stretch Marks (also known as striae graridarum) occur in the dermis, the elastic, resilient middle layer that allows skin to retain its shape. If stretch marks formed on the skin's surface, they'd be much easier to treat. When the dermis is constantly stretched over time, the skin becomes less elastic and the connective fibers break. The result is the markings we know as stretch marks. Also, when the skin is cut or scraped the injury heals but an unsightly scar will remain.



EmerginC Crease Ease Emulsion $145

An intensive, active, no-needles "line-relaxing" cream to target fine lines and creases all over the face, using clinically studied peptides, micro-collagen, herbal extracts, and a proprietary clinically-studied wild yam/soy formulation.




Dr. Michelle Copeland Rewind Eye Formula $123


Formerly known as Reparative Formula. Same great formula, brand new name.

"I'm trying not to get too excited, but I am convinced this is the best antioxidant I have seen yet," said Dr. Leslie Bauman, associate professor of dermatology at the University of Miami in the January 2004 Issue of Allure.

New breakthrough anti-wrinkle complex helps erase fine lines an wrinkles around eye, mouth and neck. A proprietary, unique blend of the most effective anti-aging agents (grape seed extract, argireline, biopeptide CL, soy, lipoic acid, DMAE, Vitamin E, ubiquinone a powerful antioxidant) has been carefully selected and formulated to stimulate cell renewal. Also contains ingredients to lighten dark circles under the eyes. Effects can be seen immediately and continue with daily use.

In the October 2004 issue of "Allure" magazine, Neil Sadick, clinical professor of dermatology at the Weil Medical School at Cornell University said, "Most antioxidants do not have scientific data to back up their claims. Idebenone does-its ability to protect cells and inhibit inflammation has been proven."

Features:
- Contains Dr. Copeland’s exclusive breakthrough anti-wrinkle complex and a unique blend of powerful anti-aging ingredients stimulates cell renewal
- For fine lines and wrinkles around eyes, mouth and neck areas
- Results are seen immediately and improvement continues with daily usage




Dermelect Empower MP6 Anti Wrinkle Treatment $79


Empower your skin. Dermelect Empower MP6 Anti-Wrinkle Treatment combines three powerful wrinkle relaxing and anti-aging peptides with hydrators, vitamins and skin synthesizers to create a wrinkle fighting solution with the highest degree of effective ingredients.

Containing the two newest multi-peptides Argireline and Matrixyl 3000, this blend of ingredients are specially formulated to safely and effectively stimulate the synthesis of its own collagen and to help soften wrinkles and fine lines from all areas of the skin.

Benefits:

- Reduces the visible severity and depth of wrinkles.
- Targets wrinkles without the loss of facial expression.
- Natural peptides provide nutritional and calming elements to the skin.
- Research shows significant skin smoothing and improvement in the appearance of wrinkle depth at both 15 and 30 days.
- Safe and non-toxic, topical alternative to injections.



BENEV Instant Lifting Serum $99


Instant Lifting Serum (ILS) is a NEW, more effective treatment to replace the popular DermaLift. This improved formula still contains the amino acid hexapeptide Argireline® to lift and tighten skin, but now it also contains a Marine Biopolymer used in traditional Eastern medicine to leave your skin feeling soft and satiny.

Research shows that, when combined with a moisturizer, Instant Lifting Serum :

- reduces the appearance of fine lines and wrinkles by 20%
- increases skin hydration by 130% in one hour
- increases skin firmness by up to 25%

For maximum effectiveness, we recommend using BENEV® Redoxa® or another premium BENEV moisturizer with Instant Lifting Serum.



HydroPeptide Intensive Concentrate Anti-Aging Corrective Creme $79


HydroPeptide Intensive Concentrate Anti-Aging Corrective Creme combines all the essential elements that make a skin care regimen effective. It's the first in its class to incorporate 3 cremes (complexes) into 1, easy-to-use formula. Each complex performs synergistically to stimulate significant results for the past, present and future of your skin.

Highly-concentrated with six peptides. Each peptide performs a distinct task at the epidermis and works indirectly with the dermis to help diminish the look of serious lines and wrinkles.

Benefits:

- Contains 3 anti-aging cremes in 1 to replenish immediately, restore over time and prevent forever.
- Peptides naturally stimulate elements of youthful skin, such as: collagen, elastin, etc.
- Antioxidants protect the skin from free radical damage and curb collagen breakdown.
- Growth factors regenerate new skin cells, blood vessels, collagen and elastin.
- Retinol helps exfoliate and speed cell turnover.
- Vitamin C promotes collagen synthesis.
- Hyaluronic acid naturally binds water for intense hydration.




Skin Healing Peptides (Copper Peptides) activate the skin’s natural healing systems. The skin repairs itself by eliminating collagen and elastin that’s been damaged over time or by environmental stressors. These peptides may help treat the signs of aging. Copper attaches itself differently to the peptides in each of the following products, but functions similarly:



Neova Advanced Perfecting Elixir by ProCyte $117

Patented AHK Copper Peptide Complex encourages a firm, youthful, radiant quality in the skin. Neova Advanced Perfecting Elixir is enriched with Hyaluronic Acid, Betaglucan and antioxidants to help support and protect the skin while polypeptides and vitamins help nourish skin. Regular use will dramatically reduce the visible signs of aging, fine lines, wrinkles, and skin blotchiness.




June Jacobs Age Defying Copper Complex $146


A powerful age-defying, anti-wrinkle cream which helps correct damaged cells and dramatically firm and moisturize fatigued skin. With continued use, it noticeably smoothes and softens the appearance of fine lines and wrinkles, and resculpts facial contours for radiant, resilient, younger-looking skin.

A powerful concentration of collagen-stimulating Copper Peptides, Proteins, Elastin, Vitamins A, C, and E, skin-fortifying antioxidants, and bioavailable hydrators that synergistically deliver gradual, continual results. This elegant, weightless formula leaves the skin plumped, taut, moist, and glowing with a matte satiny appearance. Enhances the skin's protective barrier, improves elasticity, and boost the skin's natural mechanism of renewal.




Neova Antioxidant Therapy Serum by ProCyte $98


This penetrating serum provides the skin with concentrated GHK Copper Peptide Complex and a potent combination of antioxidants. Antioxidants protect cells from environmental damage, improve the appearance of fine lines, reduce dryness, and smooth skin texture. This lightweight serum also helps diminish the appearance skin blotchiness while firming the skin.






NuFace Collagen Booster with Copper by Carol Cole $68


This product works to restore the skin's natural glow and suppleness while reducing the signs of aging. It contains an exclusive formula that works to reconstruct the collagen in human skin allowing skin cells to proliferate and restore healthy tissues.

Creams and lotions can moisturize or exfoliate the surface of the skin, but cannot diminish the lines or wrinkles that are caused by the reduction and alternation of underlying collagen support. Key ingredients, such as hydrocotyl and coneflower extracts, improve and maintain the skin's suppleness by increasing superficial and integral skin firmness and density.



Osmotics Blue Copper 5 Face Lift Serum $75


This breakthrough product delivers the ultimate lifting experience! The lightweight, yet concentrated formula combines the proven anti-aging benefits of copper peptide with the most advanced topical lifting technology available. Patented biopolymer of sweet almond proteins provide instant smoothing, toning and lifting. In addition, Shii Take mushroom extracts, clinically proven to enhance the skin's support structure, help prevent and repair thinning and sagging skin by interfering with the degradation of skin proteins. These two revolutionary ingredients enhance copper's firming and lifting action; the combination of all three delivers unprecedented results.




Osmotics Blue Copper 5 Firming Elasticity Repair $85


Osmotics' advanced research has discovered the next generation in copper technology for promoting firmer, healthier, younger looking skin. This elegant formulation combines the proven benefits of copper with our new anti-aging molecule, the 5-chain Penta-Peptide.


Benefits:

- Increases firmness, elasticity and tone.
- Promotes radiance and skin clarity for a luminous complexion.
- Increases skin's natural moisture resulting in smoother more even texture.
- Non-comedogenic, no artificial colors or fragrances.
- Perfect for all skin types, including sensitive.


Muscle Relaxing Peptides (SYN-AKE®, tripeptide) relax the facial muscles, preventing and correcting laugh lines. This new peptide, as the name suggests, is modeled after snake venom, (the Temple Viper, to be precise) but without the paralyzing effects. SYN-AKE® peptide is often powerfully combined with others, as it is in the following products:



Peter Thomas Roth UnWrinkle $120

Up to a 52% reduction in wrinkle size in just 28 days.

An exclusive, patent-pending blend of six powerful, highly concentrated, 100% active wrinkle relaxing and anti-aging peptides are combined with vitamins and skin moisturizers to create this wrinkle fighting solution with the highest degree of effective ingredients found in clinical studies.

Un-Wrinkle helps boost natural collagen production and leaves skin looking soft, smooth and years younger.

Benefits:

• Visible results after just one application.
• Up to a 52% reduction in wrinkle size in just 28 days.
• Specially formulated to target stubborn areas resistant to other treatments such as laugh lines, brow and forehead furrows.
• Helps lessen the frequency of wrinkle causing movements for firmer, more resilient skin.
• Dramatically diminishes the appearance of fine lines and wrinkles for smooth, healthy looking skin.
• Lessens the appearance of deeper, more defined wrinkles.

Key Ingredients:

• SYN®-AKE at 4% - A synthetic peptide which mimics the wrinkle relaxing properties found in snake venom.
• SNAP-8 at 10% - A safer, pain-free alternative to the injected Botulinum Toxin that topically helps target the same wrinkle formation mechanism.
• SYN®-COLL at 3% - A peptide that mimics the human body's own mechanism to produce collagen.
• Argireliner at 3% - A peptide cocktail that prevents the formation of lines and wrinkles.
• MatrixylT 3000 at 3% - A dual peptide.

This patent pending blend of six peptides is most ideal for those displaying the early signs of aging and mature skin with deeper, more defined wrinkles.

Peter Thomas Roth UnWrinkle Eye $100

The world's most advanced weapons against aging are combined in one powerful formula.

Developed for the treatment of deep wrinkles and expression lines, this revolutionary treatment utilizes the exclusive T3 Time Released Delivery System™ to deliver a highly developed cocktail of collagen activators, peptides, antioxidants, wrinkle smoothers and dermal stabilizers to the areas of the skin where and when it is needed most. This InstaLift Technology™ will give immediate results.

Benefits:

• Fades expression lines and deep wrinkles.
• Firms, tones and increases skin elasticity.
• Provides instant and long term reduction in the signs of aging
• Lifts and fills without surgery or injections with exclusive InstaLift Technology™.
• When applied under eyes, eliminates puffiness.
• Enhanced with the exclusive T3 Time Released Delivery System™.

Key Ingredients:

• 4% SYN-AKE - A synthetic peptide which mimics the muscle relaxing properties found in snake venom, allowing expression lines and deep wrinkles to fade.
• SNAP-8 - Relaxes muscles allowing expression lines and deep wrinkles to fade.
• DMAE - Firms, tones, & increases skin elasticity.
• Argerilene - A combination of peptides that fights wrinkles.
• SYN-TAKS - A dermal stabilizing peptide.
• SYN-COLL - A peptide that Stimulates collagen synthesis.
• Sodium Hyaluronate - A highly effective moisturizing agent.

Clinical Results:

• Deep wrinkles and fine lines reduced by over 58% in 28 days
• Collagen synthesis increased by 119%
• Cellular cohesion increased over 23%
• Skin tonicity improved by over 32%

Evolution Skin Therapy DeCrease Deep Wrinkle Smoothing Creme $95

UnWrinkle Eye is an exclusive, patent pending blend of six powerful, 100% active anti-aging peptides and neuropeptides that are combined with new cutting-edge ingredients created especially for the eye area. This deep wrinkle and eye expression line concentrate helps the eye area appear and feel firm and lifted.

UnWrinkle Eye is recommended for all skin types and is ideal for those who have early signs of aging and for mature skin with deeper more defined wrinkles. Ophthalmologist tested and approved. Suitable for sensitive eyes and contact lens wearers.

Proven Results:

• Visible results with just one application.
• Clinical studies have proven up to a 52% reduction in wrinkle size in 28 days.

Key Ingredients:

• SYN®-AKE at 4% - A synthetic peptide which mimics the wrinkle relaxing properties found in snake venom.
• SNAP-8 at 10% - A safer, pain-free alternative to the injected Botulinum Toxin that topically helps target the same wrinkle formation mechanism.
• SYN®-COLL at 3% - A peptide that mimics the human body's own mechanism to produce collagen.
• Argireliner at 3% - A peptide cocktail that prevents the formation of lines and wrinkles.
• MatrixylT 3000 at 3% - A dual peptide.

Peter Thomas Roth UnWrinkle Night Cream $90


This state-of-the-art moisturizer is designed to assist in cellular renewal, repair daily environmental damage, restore moisture and revitalize the skin while you sleep. Retinol helps to reduce fine lines and wrinkles and to normalize sebum production. Leaves skin looking and feeling hydrated, soft, smooth and years younger.